可穿戴柔性連續(xù)動態(tài)血糖監(jiān)測技術(shù)發(fā)展與挑戰(zhàn)
電子技術(shù)應(yīng)用
劉宇軒，曹超
山東大學(xué) 微電子學(xué)院，山東 濟(jì)南250101
摘要： 糖尿病患者群體迫切追求能夠精準(zhǔn)控糖的高質(zhì)量生活，迫切需要精準(zhǔn)、舒適的血糖監(jiān)測技術(shù)。然而傳統(tǒng)指血法只能實(shí)現(xiàn)單次有創(chuàng)采血監(jiān)測，無法滿足需求。可穿戴柔性動態(tài)葡萄糖傳感器作為下一代血糖監(jiān)測技術(shù)的重要發(fā)展方向，在糖尿病管理方面擁有巨大的應(yīng)用前景，是目前研究的熱點(diǎn)。綜述了近年來可穿戴柔性連續(xù)動態(tài)血糖監(jiān)測技術(shù)的研究現(xiàn)狀，探討了可穿戴柔性血糖傳感系統(tǒng)技術(shù)仍然面臨的挑戰(zhàn)與可能的突破方向，最后展望了可穿戴柔性血糖傳感器商業(yè)化的趨勢和未來的發(fā)展?jié)摿Α?
中圖分類號：TP212.3 文獻(xiàn)標(biāo)志碼：A DOI: 10.16157/j.issn.0258-7998.234174
中文引用格式： 劉宇軒，曹超. 可穿戴柔性連續(xù)動態(tài)血糖監(jiān)測技術(shù)發(fā)展與挑戰(zhàn)[J]. 電子技術(shù)應(yīng)用，2023，49(12)：75-84.
英文引用格式： Liu Yuxuan，Cao Chao. Development and challenges of wearable flexible continuous glucose monitoring technology[J]. Application of Electronic Technique，2023，49(12)：75-84.
中文引用格式： 劉宇軒，曹超. 可穿戴柔性連續(xù)動態(tài)血糖監(jiān)測技術(shù)發(fā)展與挑戰(zhàn)[J]. 電子技術(shù)應(yīng)用，2023，49(12)：75-84.
英文引用格式： Liu Yuxuan，Cao Chao. Development and challenges of wearable flexible continuous glucose monitoring technology[J]. Application of Electronic Technique，2023，49(12)：75-84.
Development and challenges of wearable flexible continuous glucose monitoring technology
Liu Yuxuan，Cao Chao
College of Microelectronics， Shandong University， Jinan 250101， China
Abstract： The diabetic patient group urgently pursues a high-quality life which can accurately control blood glucose, and urgently needs blood glucose monitoring technology with high precision and comfortableness. However, the traditional finger blood method can only achieve a single invasive blood glucose monitoring, which can no longer meet the demand. As an important development direction of next-generation for blood continuous glucose monitoring (CGM) technology, wearable flexible blood glucose sensor shows great potential application prospects in diabetes management, and is hot research topic. This paper reviews the research progress of wearable flexible and CGM technologies in recent years, discusses the challenges and possible breakthroughs of the wearable flexible CGM technologies, and finally prospects the trend of wearable flexible blood glucose sensor commercialization.
Key words : diabetes；blood glucose monitoring；glucose sensor；wearable technology；flexible sensor
0 引言
我國是世界范圍內(nèi)糖尿病人口最多的國家，患病率高達(dá)10.9%，算上診斷率和糖尿糖前期的比例，我國有超過一半的人口目前或未來會受到糖尿病的困擾。隨著我國老齡化社會加劇，60歲以上的患者將高達(dá)80%，每年超過100萬患者死于糖尿病相關(guān)疾病[1]；我國糖尿病患者呈現(xiàn)出三高三低的特點(diǎn)，即：發(fā)病率高、知曉率低；危害性高，治療率低；增長率高，控制率低。糖尿病的監(jiān)測與防治，目前已經(jīng)成為關(guān)系國計(jì)民生的戰(zhàn)略問題[2-3]。近年來國家出臺了一系列相關(guān)的政策和文件，如《“健康中國2030”規(guī)劃綱要》等，來促進(jìn)和強(qiáng)化糖尿病等慢病的篩查與管理，加強(qiáng)風(fēng)險(xiǎn)評估[4]。
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作者信息：
劉宇軒，曹超
（山東大學(xué) 微電子學(xué)院，山東 濟(jì)南250101）
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